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Livres
Articles (40)
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Clone controversy at Immunex

WOLFF, SHELDON M., AURON, PHILIP E., DINARELLO, CHARLES A., ROSENWASSER, LANNY J., WEBB, ANDREW C, RICH, ALEXANDER

Journal:

Nature

Année:

1986

Fichier:

PDF, 142 KB

1986

Phosphatidylinositol 3-kinase is recruited to a specific site in the activated IL-1 receptor I

Sandra Marmiroli, Alberto Bavelloni, Irene Faenza, Alessandra Sirri, Andrea Ognibene, Vittoria Cenni, Junichi Tsukada, Yoshinobu Koyama, Maria Ruzzene, Alberto Ferri, Philip E Auron, Alex Toker, Nadir

Journal:

FEBS Letters

Année:

1998

Langue:

english

Fichier:

PDF, 139 KB

english, 1998

Computer-aided nucleic acid secondary structure modeling incorporating enzymatic digestion data

Quigley, Gary J., Gehrke, Lee, Roth, David A., Auron, Philip E.

Journal:

Nucleic Acids Research

Année:

1984

Langue:

english

Fichier:

PDF, 1.17 MB

english, 1984

TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans-ubiquitination

Kent Z.Q. Wang, Deborah L. Galson, Philip E. Auron

Journal:

Journal of Cellular Biochemistry

Année:

2010

Langue:

english

Fichier:

PDF, 634 KB

english, 2010

Dietary marine lipids suppress continuous expression of interleukin-1β gene transcription1

Dwight R. Robinson, Masaharu Urakaze, Riyun Huang, Hirofumi Taki, Eiji Sugiyama, Christopher T. Knoell, LiLian Xu, Edward T. H. Yeh, Philip E. Auron

Journal:

Lipids

Année:

1996

Langue:

english

Fichier:

PDF, 1.44 MB

english, 1996

NF-IL6 and HSF1 Have Mutually Antagonistic Effects on Transcription in Monocytic Cells

Yue Xie, Changmin Chen, Mary Ann Stevenson, David A. Hume, Philip E. Auron, Stuart K. Calderwood

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 351 KB

english, 2002

157 Human IL1B Gene Induction does not Require NF-κB, but Depends Upon Long-range DNA Looping Mediated by C/EBPβ and Spi-1/PU.1

Sebnem Unlu, Kent Z.Q. Wang, Philip E. Auron

Journal:

Cytokine

Année:

2007

Langue:

english

Fichier:

PDF, 66 KB

english, 2007

IL-1-2 The IL1B gene – a viable therapeutic target for the 21st century

Philip E. Auron

Journal:

Cytokine

Année:

2010

Langue:

english

Fichier:

PDF, 132 KB

english, 2010

PS2-45 Transcriptional diversity between IL1B and TNF genes in human and murine monocytes

Juraj Adamik, Kent Z.Q. Wang, Anjey Su, Philip E. Auron

Journal:

Cytokine

Année:

2010

Langue:

english

Fichier:

PDF, 56 KB

english, 2010

The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation

Junichi Tsukada, Yasuhiro Yoshida, Yoshihiko Kominato, Philip E. Auron

Journal:

Cytokine

Année:

2011

Langue:

english

Fichier:

PDF, 1.73 MB

english, 2011

Glucocorticoid inhibits the human pro-interleukin lβ gene (ILIB) by decreasing DNA binding of transactivators to the signal-responsive enhancer

Wayne R. Waterman, Li Lian Xu, Sotirios Tetradis, Gabriela Motyckova, Junichi Tsukada, Kazuyoshi Saito, Andrew C. Webb, Dwight R. Robinson, Philip E. Auron

Journal:

Molecular Immunology

Année:

2006

Langue:

english

Fichier:

PDF, 341 KB

english, 2006

Phosphorylation of IRF8 in a pre-associated complex with Spi-1/PU.1 and non-phosphorylated Stat1 is critical for LPS induction of the IL1B gene

Sebnem Unlu, Arvind Kumar, Wayne R. Waterman, Junichi Tsukada, Kent Z.Q. Wang, Deborah L. Galson, Philip E. Auron

Journal:

Molecular Immunology

Année:

2007

Langue:

english

Fichier:

PDF, 992 KB

english, 2007

Inhibition of IL-1β transcription by peptides derived from the hCMV IE2 transactivator

James A. Listman, JoAnne E. Race, Nancy Walker-Kopp, Sebnem Unlu, Philip E. Auron

Journal:

Molecular Immunology

Année:

2008

Langue:

english

Fichier:

PDF, 800 KB

english, 2008

Dual regulatory role of human cytomegalovirus immediate-early protein in IL1B transcription is dependent upon Spi-1/PU.1

Zhiyong Yang, Nawarat Wara-aswapati, Yasuhiro Yoshida, Nancy Walker, Deborah L Galson, James Listman, Philip E Auron

Journal:

Biochemical and Biophysical Research Communications

Année:

2002

Langue:

english

Fichier:

PDF, 201 KB

english, 2002

Characterization of a cascade of protein interactions initiated at the IL-1 receptor

Jason A Boch, Yasuhiro Yoshida, Yoshinobu Koyama, Nawarat Wara-Aswapati, Hiabing Peng, Sebnem Unlu, Philip E Auron

Journal:

Biochemical and Biophysical Research Communications

Année:

2003

Langue:

english

Fichier:

PDF, 286 KB

english, 2003

The Interleukin 1 Receptor: Ligand Interactions and Signal Transduction

Philip E. Auron

Journal:

Cytokine & Growth Factor Reviews

Année:

1998

Langue:

english

Fichier:

PDF, 3.35 MB

english, 1998

The role of TNF-receptor family members and other TRAF-dependent receptors in bone resorption

Ellen M Gravallese, Deborah L Galson, Steven R Goldring, Philip E Auron

Journal:

Arthritis Research & Therapy

Année:

2000

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2000

2

Adamik, Juraj, Tannahill, Gillian M., Su, An-Jey A., O’Neill, Luke A., Galson, Deborah L., Auron, Philip E.

Journal:

Cytokine

Année:

2013

Langue:

english

Fichier:

PDF, 182 KB

english, 2013

Chromosomal organization and localization of the human urokinase inhibitor gene: Perfect structural conservation with ovalbumin

Samia, Julie A., Alexander, Susan J., Horton, Kristin W., Auron, Philip E., Byers, Mary G., Shows, Thomas B., Webb, Andrew C.

Journal:

Genomics

Année:

1990

Langue:

english

Fichier:

PDF, 1.07 MB

english, 1990

[Part 1: Biological Sciences] || Nucleotide Sequence of Human Monocyte Interleukin 1 Precursor cDNA

Philip E. Auron, Andrew C. Webb, Lanny J. Rosenwasser, Steven F. Mucci, Alexander Rich, Sheldon M. Wolff and Charles A. Dinarello

Journal:

Proceedings of the National Academy of Sciences

Année:

1984

Langue:

english

Fichier:

PDF, 1.38 MB

english, 1984

Expression of Biologically Active Human Interleukin 1 Subpeptides by Transfected Simian COS Cells

Lanny J. Rosenwasser, Andrew C. Webb, Burton D. Clark, Shinkichi Irie, Lauren Chang, Charles A. Dinarello, Lee Gehrke, Sheldon M. Wolff, Alexander Rich and Philip E. Auron

Journal:

Proceedings of the National Academy of Sciences

Année:

1986

Langue:

english

Fichier:

PDF, 804 KB

english, 1986

Negative Cross-Talk between Hematopoietic Regulators: GATA Proteins Repress PU.1

Pu Zhang, Gerhard Behre, Jing Pan, Atsushi Iwama, Nawarat Wara-Aswapati, Hanna S. Radomska, Philip E. Auron, Daniel G. Tenen and Zijie Sun

Journal:

Proceedings of the National Academy of Sciences

Année:

1999

Langue:

english

Fichier:

PDF, 1.26 MB

english, 1999

The IL17A and IL17F loci have divergent histone modifications and are differentially regulated by prostaglandin E2 in Th17 cells

Adamik, Juraj, Henkel, Matthew, Ray, Anuradha, Auron, Philip E., Duerr, Richard, Barrie, Arthur

Journal:

Cytokine

Année:

2013

Langue:

english

Fichier:

PDF, 958 KB

english, 2013

5'-Conformation of capped alfalfa mosaic virus ribonucleic acid may reflect its independence of the cap structure or of cap-binding protein for efficient translation

Gehrke, Lee, Auron, Philip E., Quigley, Gary J., Rich, Alexander, Sonenberg, Nahum

Journal:

Biochemistry

Année:

1983

Langue:

english

Fichier:

PDF, 2.00 MB

english, 1983

Multiple amino acid substitutions suggest a structural basis for the separation of biological activity and receptor binding in a mutant human interleukin-1.beta. protein

Auron, Philip E., Quigley, Gary J., Rosenwasser, Lanny J., Gehrke, Lee

Journal:

Biochemistry

Année:

1992

Langue:

english

Fichier:

PDF, 2.25 MB

english, 1992

Comparison of transfer ribonucleic acid structures using cobra venom and S1 endonucleases

Auron, Philip E., Weber, Lawrence D., Rich, Alexander

Journal:

Biochemistry

Année:

1982

Langue:

english

Fichier:

PDF, 3.26 MB

english, 1982

Measuring Immunity || DNA Sequence-Specific Transcription Factors

Auron, Philip E.

Année:

2005

Langue:

english

Fichier:

PDF, 2.68 MB

english, 2005

Computer-aided prediction of RNA secondary structures

Auron, Philip E., Rindone, Wayne P., Vary, Calvin P.H., Celentano, James J., Vournakis, John N.

Journal:

Nucleic Acids Research

Année:

1982

Langue:

english

Fichier:

PDF, 557 KB

english, 1982

Heat Shock Factor 1 Represses Transcription of the IL-1β Gene through Physical Interaction with the Nuclear Factor of Interleukin 6

Xie, Yue, Chen, Changmin, Stevenson, Mary Ann, Auron, Philip E., Calderwood, Stuart K.

Journal:

Journal of Biological Chemistry

Année:

2002

Langue:

english

Fichier:

PDF, 757 KB

english, 2002

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

Clark, Burton D., Collins, Kathleen L., Gandy, Melinda S., Webb, Andrew C., Auron, Philip E.

Journal:

Nucleic Acids Research

Année:

1987

Langue:

english

Fichier:

PDF, 55 KB

english, 1987

Genomic sequence for human prointerleukin 1 beta: possible evolution from a reverse transcribed prointerleukin 1 alpha gene

Clark, Burton D., Collins, Kathieen L., Gandy, Melinda S., Webb, Andrew C., Auron, Philip E.

Journal:

Nucleic Acids Research

Année:

1986

Langue:

english

Fichier:

PDF, 2.14 MB

english, 1986

DNA Familial Binding Profiles Made Easy: Comparison of Various Motif Alignment and Clustering Strategies

Mahony, Shaun, Auron, Philip E., Benos, Panayiotis V.

Journal:

PLoS Computational Biology

Année:

2007

Langue:

english

Fichier:

PDF, 1.05 MB

english, 2007

Cloning and Functional Analysis of the Mouse 5-Lipoxygenase Promoter

Silverman, Eric S., Le, Louis, Baron, Rebecca M., Hallock, Arlene, Hjoberg, Josephine, Shikanai, Toshiki, Storm van's Gravesande, Karin, Auron, Philip E., Lu, Weining

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

2002

Langue:

english

Fichier:

PDF, 210 KB

english, 2002

The Immediate Early Genes of Human Cytomegalovirus Require Only Proximal Promoter Elements to Upregulate Expression of Interleukin-1 β

Crump, John W., Geist, Lois J., Auron, Philip E., Webb, Andrew C., Stinski, Mark F., Hunninghake, Gary W.

Journal:

American Journal of Respiratory Cell and Molecular Biology

Année:

1992

Langue:

english

Fichier:

PDF, 497 KB

english, 1992

The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1alpha, Jak1 and Jak2

OSAKI, Makoto, TAN, Lujian, CHOY, Bob K., YOSHIDA, Yasuhiro, CHEAH, Kathryn S.E., AURON, Philip E., GOLDRING, Mary B.

Journal:

Biochemical Journal

Année:

2003

Langue:

english

Fichier:

PDF, 289 KB

english, 2003

Cytomegalovirus IE2 Protein Stimulates Interleukin 1β Gene Transcription via Tethering to Spi-1/PU.1

Wara-aswapati, Nawarat, Yang, Zhiyong, Waterman, Wayne R., Koyama, Yoshinobu, Tetradis, Sotirios, Choy, Bob K., Webb, Andrew C., Auron, Philip E.

Journal:

Molecular and Cellular Biology

Année:

1999

Langue:

english

Fichier:

PDF, 489 KB

english, 1999

Distinct Mechanisms for Induction and Tolerance Regulate the Immediate Early Genes Encoding Interleukin 1β and Tumor Necrosis Factor α

Adamik, Juraj, Wang, Kent Z. Q., Unlu, Sebnem, Su, An-Jey A., Tannahill, Gillian M., Galson, Deborah L., O’Neill, Luke A., Auron, Philip E., Yan, Chunhong

Journal:

PLoS ONE

Année:

2013

Langue:

english

Fichier:

PDF, 4.46 MB

english, 2013

Human papillomavirus type 16 antagonizes IRF6 regulation of IL-1β

Ainouze, Michelle, Rochefort, Pauline, Parroche, Peggy, Roblot, Guillaume, Tout, Issam, Briat, François, Zannetti, Claudia, Marotel, Marie, Goutagny, Nadege, Auron, Philip, Traverse-Glehen, Alexandra,

Journal:

PLoS Pathogens

Année:

2018

Langue:

english

Fichier:

PDF, 3.20 MB

english, 2018

Distinct mechanisms regulate IL1B gene transcription in lymphoid CD4 T cells and monocytes

Pulugulla, Sree H., Packard, Thomas A., Galloway, Nicole L.K., Grimmett, Zachary W., Doitsh, Gilad, Adamik, Juraj, Galson, Deborah L., Greene, Warner C., Auron, Philip E.

Journal:

Cytokine

Année:

2018

Langue:

english

Fichier:

PDF, 1.52 MB

english, 2018

Constitutive activation of LIL-Stat in adult T-cell leukemia cells

Tsukada, Junichi, Toda, Yoko, Misago, Masahiro, Tanaka, Yoshiya, Auron, Philip E., Eto, Sumiya

Journal:

Blood

Année:

2000

Fichier:

PDF, 154 KB

2000